Gene ML0427c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameorn
Gene length648 bp
IdentifierML0427c
Location 526295 bp
Protein summary information
Molecular mass23684.7 Da
Isoelectric point4.48
Protein length216 amino acids
Structural information
PFAMPF00929
Orthologs
M. tuberculosis H37RvRv2511
M. lepromatosis Mx1-22AMLPM_0427
Cross-references
UniProtO07708
Gene OntologyExoribonuclease activity, producing 5'-phosphomonoesters, Nucleic acid binding, Cytoplasm
Enzyme Classification3.1.-.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable oligoribonuclease Orn
CommentsML0427c, len: 215 aa. Probable orn, oligoribonuclease (EC 3.1.-.-), highly similar to Rv2511|ORN_MYCTU|O06174 orn, probable oligoribonuclease from M. tuberculosis (215 aa), Fasta scores: E(): 0, (84.5% identity in 213 aa overlap). Similar to many others e.g. ORN_ECOLI|P39287 orn, oligoribonuclease from Escherichia coli (180 aa), Fasta scores: E(): 8.2e-25, (45.3% identity in 172 aa overlap). Previously sequenced as ORN_MYCLE|O07708 (215 aa), Fasta scores: E(): 0, (99.5% identity in 215 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS526295526942-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0427c|orn
VHDELVWIDCEMTGLDLGSDQLIEIAALVTDADLNILGDGVDVVIHIDSTALSSMIDVVAEMHSRSGLINEVESSIVDLVTAESIVLDYINNHVKQPKTAPLAGNSIATDRSFIARDMPTLDSFLHYRMIDVSSIKELCRRWYPRIYFGQPAKGLTHRALADIHESIRELRFYRRTAFVPPPGPSTREIAEVVADLSGTPATPGDIDSAYERPNG
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