Gene ML0430 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0430
Gene length1365 bp
IdentifierML0430
Location 529521 bp
Protein summary information
Molecular mass47630.1 Da
Isoelectric point10.45
Protein length455 amino acids
Structural information
PFAMPF07690
Orthologues
M. tuberculosisRv2508c
Cross-references
UniProtQ9CCU4
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved integral membrane leucine and alanine rich protein
CommentsML0430, len: 454 aa. Probable conserved integral membrane leu-, ala-rich protein, highly similar to Rv2508c|O06171|AL123456 conserved integral membrane from M. tuberculosis (445 aa), Fasta scores: E(): 0, (75.7% identity in 441 aa overlap). Also similar to hypothetical or membrane proteins e.g. Q9RKX9|AL133213|SC6D7.19C putative integral membrane protein from Streptomyces coelicolor (486 aa), Fasta scores: E(): 1.5e-13, (29.7% identity in 445 aa overlap). Previously sequenced as O07710|Z97179 (464 aa), Fasta scores: E(): 0, (100.0% identity in 454 aa overlap). Contains hydrophobic, possible membrane-spanning regions.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS529521530885+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0430|ML0430
MNQPESVAGTMVRSWVVAWAMWDCGSTGLTAIVATFVFSVYLTSSVGVGMPDGISLVSWLGRAGAVAGLTIAVLAPAIGVWVESPHRRRVTLGVLTVLAVALTCGMSFIRDQPSYLWAGLMLLAGTAACGDLASVPYNAMLRQLSTPATAGRISGLGWASGYVGSVVLLLLIYLGFISGTGELRGLLQLPTHDGIYVRAAMLLAAAWLALLALPLLLTAHRLPSLGEVSHPTSMLGGYRKLWSEVSAEWRRDRNLVYFLVASALFRDGLAATLGFGAVLGVNAYGISQANVLMFGVVASLVAAVGAVLGGFVDHRIGSKRVIVGSLVAIIVTALTLMTLSGPLAFWVCGLVLCLFIGPSQSSSRALLLHMAKHGREGVAFGLYTMTGRAASFVAPWSFSIFVDGFGVVRAGLGGISVVLLAGLLGMLMVRVPTRREAAAVGLSWWRSQARRGQV
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