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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved integral membrane leucine and alanine rich protein
CommentsML0430, len: 454 aa. Probable conserved integral membrane leu-, ala-rich protein, highly similar to Rv2508c|O06171|AL123456 conserved integral membrane from M. tuberculosis (445 aa), Fasta scores: E(): 0, (75.7% identity in 441 aa overlap). Also similar to hypothetical or membrane proteins e.g. Q9RKX9|AL133213|SC6D7.19C putative integral membrane protein from Streptomyces coelicolor (486 aa), Fasta scores: E(): 1.5e-13, (29.7% identity in 445 aa overlap). Previously sequenced as O07710|Z97179 (464 aa), Fasta scores: E(): 0, (100.0% identity in 454 aa overlap). Contains hydrophobic, possible membrane-spanning regions.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS529521530885+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0430|ML0430
MNQPESVAGTMVRSWVVAWAMWDCGSTGLTAIVATFVFSVYLTSSVGVGMPDGISLVSWLGRAGAVAGLTIAVLAPAIGVWVESPHRRRVTLGVLTVLAVALTCGMSFIRDQPSYLWAGLMLLAGTAACGDLASVPYNAMLRQLSTPATAGRISGLGWASGYVGSVVLLLLIYLGFISGTGELRGLLQLPTHDGIYVRAAMLLAAAWLALLALPLLLTAHRLPSLGEVSHPTSMLGGYRKLWSEVSAEWRRDRNLVYFLVASALFRDGLAATLGFGAVLGVNAYGISQANVLMFGVVASLVAAVGAVLGGFVDHRIGSKRVIVGSLVAIIVTALTLMTLSGPLAFWVCGLVLCLFIGPSQSSSRALLLHMAKHGREGVAFGLYTMTGRAASFVAPWSFSIFVDGFGVVRAGLGGISVVLLAGLLGMLMVRVPTRREAAAVGLSWWRSQARRGQV
      
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