Gene ML0486 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameyajC
Gene length345 bp
IdentifierML0486
Location 589653 bp
Protein summary information
Molecular mass12749.4 Da
Isoelectric point3.92
Protein length115 amino acids
Structural information
PFAMPF02699
Orthologs
M. tuberculosis H37RvRv2588c
M. lepromatosis Mx1-22AMLPM_0486
Cross-references
UniProtQ49647
Gene OntologyExtracellular region
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable conserved membrane protein secretion factor YajC
CommentsML0486, len: 114 aa. Probable yajC, a conserved membrane protein secretion factor, (see Braunstein & Belisle 2000), highly similar to YP88_MYCTU|Q50633|Rv2588c Probable yajC, secretion factor from M. tuberculosis (115 aa), Fasta scores: E(): 7e-29, (77.0% identity in 100 aa overlap); and CAD94804|Mb2619c from M. bovis (115 aa). Similar to other bacterial proteins e.g. Q9L292|SCL2.07c putative secreted protein from Streptomyces coelicolor (169 aa), Fasta scores: E(): 7.3e-08, (35.8% identity in 120 aa overlap). Previously sequenced as YP88_MYCLE|Q49647 (114 aa), Fasta scores: E(): 0, (100.0% identity in 114 aa overlap). Contains a possible N-terminal signal sequence.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS589653589997+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0486|yajC
MESLVLLLLFLLIMGGFMFFASRRQRRSMQATIDLYNSLQPGDRVNTTSGLQATIIVVGDDTVDLEIAPGVVTTWMKLAIRDRILPDDAYMDEHEAEPGDFVYCDELEESDGSS
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