Gene ML0488
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable protein-export membrane protein SecF |
| Comments | ML0488, len: 471 aa. Probable secF, protein-export membrane protein (integral membrane protein) (see citation below), highly similar to SECF_MYCTU|Q50635|Rv2586c secF, putative protein-export membrane protein from M. tuberculosis (442 aa), Fasta scores: E(): 0, (72.1% identity in 456 aa overlap); and CAD94802|Mb2617c from M. bovis (442 aa). Similar to others e.g. Q9AE06|SECF from Corynebacterium glutamicum (Brevibacterium flavum) (403 aa), FASTA scores: E(): 1.8e-67, (46.024% identity in 415 aa overlap); and Q53956|SECF_STRCO|SCL2.05c from Streptomyces coelicolor (373 aa), FASTA scores: E(): 3e-33, (35.941% identity in 409 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Belongs to the secD/secF family, secF family. Part of the prokaryotic protein translocation apparatus which comprises SecA1|ML0799, SecA2|ML2082c, SecD|ML0487, secG|ML0577, SecE|ML1907, SecF|ML0488 and SecY|ML1833. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 591835 | 593250 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0488|secF
MVSRAKVGAETTKGIDEPDRNDNTDDNGAGAVEVTEAAEDAVELTNDISTQLPQHGFLARFYTGLSRLYTGTGVFEVVGRRRLWYSVGGVIVAVAVLSIIVRGFTFGIDFKGGTTVSMPVSPGVGGTGAIEVAQVADVFKKTLGSDPESVVVVGNGASATVRISSKTLSNDQTSKLRNALFDAFGPKGADAKPSKQAISDAAVSETWGGQITKKVVIALVVFLVLVGLYITVRYERYMAISALTTMCFDLTVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTHGFQHTTRRTFAEQANLAINQTFMRSINTSLISVLPVLALMVVAVWLLGVGTLKDLALVQLVGIIVGTYSSIFFATPLLVTLRERTELVRTHTRRVVKRRTLGSQVGKKNADSHVAAGTRKPQNQAESCADASSQEGTEVATASVPTVLSKLAPGVRPVRPTGTRRPTGKRNNVGRR
Bibliography
No article yet recorded
