Gene ML0508 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0508
Gene length942 bp
IdentifierML0508
Location 617502 bp
Protein summary information
Molecular mass34713.8 Da
Isoelectric point5.02
Protein length314 amino acids
Structural information
PFAMPF01841, PF08379
Orthologs
M. tuberculosis H37RvRv2569c
M. lepromatosis Mx1-22AMLPM_0508
Cross-references
UniProtQ9CCT2
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductConserved hypothetical protein
CommentsML0508, len: 313 aa. Conserved hypothetical protein, highly similar to YP69_MYCTU|Q50652|Rv2569c conserved hypothetical protein from M. tuberculosis (314 aa), Fasta scores: E(): 0, (84.4% identity in 301 aa overlap); and CAD94784|Mb2599c from M. bovis (314 aa). And similar to other hypothetical proteins e.g. Q9HUN8|PA4926 from Pseudomonas aeruginosa (311 aa), FASTA scores: E(): 1.3e-35, (36.774% identity in 310 aa overlap). Also similar to ML0607 and Rv2409c from M. tuberculosis. Contains Pfam match to entry PF01841 Transglut_core, Transglutaminase-like superfamily.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS617502618443+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0508|ML0508
MLSCHMKWTQLTSRRYRVSHRTEYRYSDVVTSSYGRGFLTPCDSLRQRCVDHRLHIVPVPADSSISRDSYGNISSYFHVTEPHCTLTVTSESIVDVYPTPPELFTSGPASAPWEAARPTGRRGVLATEFTLDLNPPEITDEVRQYAAPSFEPQRPLIEVLRDLTTRIYADFTYRSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAASYVSGYLATDPPPGKDRMVGIDVTHAWASVWTPQQSGQCEWLGLDPTNDQLVDERYIVVGQGRDYVNVPPLRGIIYTNSENSVIDVAVDVAPCEGDALYA
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