Gene ML0543 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedfp
Gene length1260 bp
IdentifierML0543
Location 658334 bp
Protein summary information
Molecular mass44212.4 Da
Isoelectric point6.32
Protein length420 amino acids
Structural information
PFAMPF02441, PF04127
Orthologs
M. tuberculosis H37RvRv1391
M. lepromatosis Mx1-22AMLPM_0543
Cross-references
UniProtQ9CCQ5
Gene OntologyCoenzyme a biosynthetic process, Pantothenate catabolic process, Phosphopantothenate--cysteine ligase activity, Phosphopantothenoylcysteine decarboxylase activity, Fmn binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable DNA/pantothenate metabolism flavoprotein homolog Dfp
CommentsML0543, len: 419 aa. Probable dfp, DNA/pantothenate metabolism flavoprotein homolog, highly similar to DFP_MYCTU|P71661|Rv1391 probable dfp, DNA/pantothenate metabolism flavoprotein homolog from M. tuberculosis (418 aa), Fasta scores: E(): 1.8e-139, (87.0% identity in 409 aa overlap); and CAD94287|Mb1426 from M. bovis (418 aa). Similar to many e.g. DFP_ECOLI|P24285 dfp, DNA/pantothenate metabolism flavoprotein from Escherichia coli (430 aa), Fasta scores: E(): 0, (39.7% identity in 408 aa overlap). Contains match to Pfam entry PF02441 Flavoprotein.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS658334659593+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0543|dfp
MDCKRVVVGVSGGIAAYKACTVVRQLIDAGHEVRVIPTESALRFVGTATFEALSGQPVYTDVFDDIPAVSHVYLGKQADLVVVAPATADLLARAVHGRADDLLTATLLTARCPIMFAPAMHTEMWLHPATVDNVATLRRRGAIVLEPASGRLTGTDSGAGRLPEAEEITTLAQLLLERHDALPYDLTGRKLLVTSGGTRESIDPVRFIGNRSSGKQGYAVARVAVQRGAEVTLIAGHTAGLTNPAGVDVVHVGSAQQLGDAVSKHAPDFDVLVMAAAVADFRPAQVATAKIKKGPDDQDEPLIELVYNEDVLAAAVRARTHGQLPNMRAIVGFAAETGDASGDVLFHARAKLRRKGCDLLVVNAVGDGRAFEVDNNDGWLLASDGTELALQHGSKMLMASRIVDGIVTFLHGLPDLRGG
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