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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable protein-export membrane protein (Translocase subunit) SecG
CommentsML0577, len: 77 aa. Probable secG, protein-export membrane protein (translocase subunit) (see citation below), highly similar to SECG_MYCTU|O06819|Rv1440 secG, probable protein-export membrane protein from M. tuberculosis (77 aa), Fasta scores: E(): 1.1e-25, (96.1% identity in 77 aa overlap); and CAD96142|Mb1475 from M. bovis (77 aa). Similar to many e.g. Q9Z521|SECG_STRCO Protein-export membrane protein from Streptomyces coelicolor (102 aa), fasta scores: E(): 3.9e-12, (53.425% identity in 73 aa overlap). Previously sequenced as SECG_MYCLE|P38388 (77 aa), Fasta scores: E(): 3.1e-26, (100.0% identity in 77 aa overlap). Contains hydrophobic, possible membrane-spanning regions. Part of the prokaryotic protein translocation apparatus which comprises SecA1|ML0799, SecA2|ML2082c, SecD|ML0487, secG|ML0577, SecE|ML1907, SecF|ML0488 and SecY|ML1833.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS699951700184+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0577|secG
MELALQITLVVTSILVVLLVLLHRAKGGGLSTLFGGGVQSSLSGSTVVEKNLDRLTLFVTGIWLVSIIGVALLTKYR
      
Bibliography
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