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information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable chaperone protein DnaJ2
CommentsML0625, len: 378 aa. Probable dnaJ2, chaperone protein, highly similar to O05825|AL123456|Rv2373c Probable dnaJ2, chaperone protein from M. tuberculosis (382 aa), Fasta scores: E(): 1.7e-138, (88.0% identity in 382 aa overlap); and CAD97255|Mb2394c from M. bovis (382 aa). Similar to many e.g. Q9RDD7|DNJ2_STRCO Chaperone protein dnaJ2 from Streptomyces coelicolor (378 aa), fasta scores: E(): 1.2e-83, (54.068% identity in 381 aa overlap); and DNAJ_ECOLI|P08622 dnaJ, Dna protein from Escherichia coli (375 aa), Fasta scores: (40.6% identity in 382 aa overlap). Also similar to ML2494. Previously sequenced as Q49762|U00016 (378 aa), Fasta scores: E(): 0, (99.7% identity in 378 aa overlap). Contains Pfam match to entry PF01556 DnaJ_C, DnaJ C terminal region. Contains Pfam match to entry PF00684 DnaJ_CXXCXGXG, DnaJ central domain (4 repeats). Contains Pfam match to entry PF00226 DnaJ, DnaJ domain. Belongs to the DNAJ family.
Functional category-
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS757874759010+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0625|dnaJ2
VARDYYGLLGVSRNASDADIKRAYRKLARELHPDINPDEAAQAKFKEISMAYEVLSDPEKRRIVDLGGDPMENAAASPSGFGGFGGLGDVFEAFFGGSSASRGPIGRVRPGSDSLLPMWLDLEECATGVTKQVTVDTAVLCDRCQGKGTNGDSAPIPCDTCGGRGEVQTVQRSLLGQMVTARPCPTCRGVGVVIPDPCCQCVGDGRVRARREITVKIPSGVGDGMRVRLAAQGEVGPGGGPAGDLYVEVHEQAHDIFVRDGDDLHCTVSVPMVDAALGTTITVDAILDGMSEIDISPGTQPGSVIELRGQGMPHLRSNTRGNLHVHVEVMVPTRLDQHDTELLRELKRRRSRDVAEVRSTHAAGGGLFSRLRETFTNR
      
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