Gene ML0627 (phoH)
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable phoH-like protein PhoH1 (Phosphate starvation-inducible protein PsiH) |
| Comments | ML0627, len: 329 aa. Probable phoH1, phoH-like protein (phosphate starvation-induced protein), probably ATP-binding protein, highly similar to PHOL_MYCTU|O05830|Rv2368c phoH, phoH-family protein from M. tuberculosis (352 aa), Fasta scores: E(): 1.4e-116, (88.9% identity in 352 aa overlap); and CAD97250|Mb2389c from M. bovis (352 aa). Similar to others e.g. PHOH_ECOLI|P31544 phoH, phosphate starvation-inducible protein from Escherichia coli (354 aa), Fasta scores: E(): 1.2e-29, (36.8% identity in 304 aa overlap). Some similarity to ML1951 from M. leprae. Previously sequenced as PHOL_MYCLE|Q49751 (349 aa), Fasta scores: E(): 0, (99.7% identity in 349 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the PhoH family. Note that previously known as phoH. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 760115 | 761164 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0627|phoH1
VTHHETSAVDASSASMHVRSTIDVPPDLVVGLLGSADENLRALERMLSADLHVRGNTVAFSGEPADVALAERAISELVAIVASGHPLTPEVVRHGVAMLVGTGNESPAEVLTLDILLRRGKTVRPKTLNQKRYVDAIDANTIVFGIGPAGTGKTYLAMAKAVNALQTKQVTRIILTRPAVEAGERLGFLPGTLSEKIDPYLRPLYDALYDMMDPELIPKLMSSGVIEVASLAYMRGRTLNDAFIVLDEAQNTTAEQMKMFLTRLGFGSKVVVTGDVTQIDLPGGARSGLRAAVDILEHIDDIYVAELASVDVVRHRLVSEIVDAYAEYEEHDLGMNRAARRASGARNRR
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