Gene ML0691c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable D-alanyl-D-alanine carboxypeptidase DacB1 (PENICILLIN-BINDING PROTEIN) (DD-PEPTIDASE) (DD-CARBOXYPEPTIDASE) (PBP) (DD-TRANSPEPTIDASE) (SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE) (D-AMINO ACID HYDROLASE) |
| Comments | ML0691c, len: 411 aa. Probable dacB1, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein) (EC 3.4.16.4), highly similar to O53380|AL123456|Rv3330 dacB1, D-alanyl-D-alanine carboxypeptidase from M. tuberculosis (405 aa), Fasta scores: E(): 0, (77.2% identity in 416 aa overlap); and CAD95475|Mb3363 from M. bovis (405 aa). Similar to several e.g. Q8FRR0 Putative penicillin-binding protein from Corynebacterium efficiens (447 aa), fasta scores: E(): 1.6e-50, (45.283% identity in 371 aa overlap). Previously sequenced as Q49917|U00022 (228 aa), Fasta scores: E(): 0, (100.0% identity in 228 aa overlap). Contains a probable N-terminal signal sequence. Contains Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase. BELONGS TO PEPTIDASE FAMILY S11; ALSO KNOWN AS THE D-ALANYL-D-ALANINE CARBOXYPEPTIDASE 1 FAMILY |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 827878 | 829113 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0691c|dacB1
MSFLRSTACLAAAVFAIVGPVALDLPTAVPVGHAEPNAGPNAGPATCPYQVSTPPAVDSSEVPQTGNPPMPLAVPPKPVGGAALNSCGIVTAPDTPPVPGDLSAEAWLVADLNSGAVIAARDPHGRHRPASIIKVLLAMASINTLNLNKSVAGTAEDAAAEGTKVGVHDGGTYTINQLLHGLLMQSGNDAAHSLAMQLGGMQQALQKINVLAAKLGGQDTRVATPSGLDGPGMSTSAYDIGLFYRYAWQNPSFSNIVATRTFNFPGPGDHPGYQLENDNQLLYQYPGALGGKTGYTDDAGQTFVGAANRNGRRLMAVLLHGTRQPIAPWEQAAHLLDYGFSTAVGTQIGTLIEPDPTVAGNADRHGHGLQAAGIMSSNDTLPVRIGVAVVGTLIVFGLIMITRSLNRRPQH
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