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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductProbable succinate dehydrogenase (cytochrome B-556 subunit) SdhC (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)
CommentsML0699c, len: 153 aa. Probable sdhC, cytochrome B-556 of succinate dehydrogenase SdhC subunit (EC 1.3.99.1), transmembrane protein, highly similar but longer than O53368|AL123456|Rv3316 sdhC, cytochrome B-556 of succinate dehydrogenase from M. tuberculosis (112 aa), Fasta scores: E(): 0, (88.4% identity in 112 aa overlap); and CAD95437|Mb3345 from M. bovis (112 aa). Similar to many e.g. Q9KZ88 Putative succinate dehydrogenase membrane subunit from Streptomyces coelicolor (126 aa), fasta scores: E(): 5.4e-24, (57.273% identity in 110 aa overlap). Previously sequenced as Q49919|U00022 (244 aa), Fasta scores: E(): 0, (100.0% identity in 153 aa overlap). Contains Pfam match to entry PF01127 Sdh_cyt, Succinate dehydrogenase cytochrome b subunit. PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC ANCHOR PROTEIN. BELONGS TO THE CYTOCHROME B560 FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS836930837391-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0699c|sdhC
VRTTATPANPATSRPVAASSRRRRPPTTTYRGDPGMWSWVLHRISGATIFFFLFVHVLDAAMLRVNPQTYNAVLSTYKAPIVGFMEYGLVAAVGFHGLNGIRVILIDFWSEGPRHQRLMLWIISVIFLLLLVPAGVVIGIHMWEHFRMWEHFR
      
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