Gene ML0706c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable phosphomannomutase PmmB (PHOSPHOMANNOSE MUTASE) |
| Comments | ML0706c, len: 538 aa. Probable pmmB, phosphomannomutase (EC 5.4.2.8), highly similar to O53360|AL123456|Rv3308 pmmB, probable phosphomannomutase from M. tuberculosis (534 aa), Fasta scores: E(): 0, (76.8% identity in 538 aa overlap); and CAD95428|Mb3336 from M. bovis (534 aa). Similar to several e.g. Q9AD82 Putative phosphomannomutase from Streptomyces coelicolor (549 aa), E(): 3e-78, (46.154% identity in 533 aa overlap). Shows weak similarity to ML0366 and ML0763. Previously sequenced as Q49913|U00022 (534 aa), Fasta scores: E(): 0, (99.8% identity in 534 aa overlap). Contains Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase. Contains PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. BELONGS TO THE PHOSPHOHEXOSE MUTASES FAMILY. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 843848 | 845464 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0706c|pmmB
LKAAVTPEEWITHDPDPQTAAELAACDPDELAARFTRALRFGTSGLRGPVRGGPDAMNLAVVLRATWAVAQVLLQRAGSRPATVIVGRDSRHGSAAFVAATAEVLAAEGFSVLLLPNPAPTPVVAFAVRNTGAAAGIQITASHNPPTDNGYKVYFDGGIQIISPIDHQIENAMAAAPLADQITRKPVNPSENSASDLVDHYIQRAAAVRRSNGSVRVALTPMHGVGGAVAVETLRRTGFDDVHTVAAQFEPDPDFPTVAFPNPEEPGATDALLALAAHVGADVAIALDPDADRCAVGIPTNSGWRMLSGDETGWLLGDYILSQTDKPETAVVASTVVSSRMLPAIATHYNAVHVETLTGFKWLARADANLPGTLVYAYEEAIGHCVDPTAVRDKDGISAAVLVCDLVAALHKQGRSVPDMLDQLALRHGVHDVTAISRRIGPKQTGVDEAVDLIQRLRAAPPSQLAGFTATTTDITDALIFTGGDDDTWVRVVVRLSGTEPKLKCYLEVRCSVAGNLPSTRQRARVLRDELVTLVQQW
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