Gene ML0760 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namewhiB2
Gene length270 bp
IdentifierML0760
Location 903228 bp
Protein summary information
Molecular mass10119.4 Da
Isoelectric point5.23
Protein length90 amino acids
Structural information
PFAMPF02467
Orthologs
M. tuberculosis H37RvRv3260c
M. lepromatosis Mx1-22AMLPM_0760
Cross-references
UniProtQ9CCK0
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable transcriptional regulatory protein WhiB-like WhiB2
CommentsML0760, len: 89 aa. Probable whiB2 (alternate gene name: whmD), WhiB-like regulatory protein (see Hutter & Dick 1999), similar to Q53963|X62287 WhiB paralogue of Streptomyces coelicolor (85 aa), fasta scores: E(): 4.8e-26, (85.5% identity in 69 aa overlap). Highly similar to Rv3260c|MTV015.05c|O53353|AL021840 whiB2 regulatory protein from Mycobacterium tuberculosis (89 aa), fasta scores: E(): 0, (85.4% identity in 89 aa overlap); to Q9S426|AF164439 whmD regulatory protein (see Gomez & Bishai 2000) from Mycobacterium smegmatis (129 aa), fasta scores: E(): 1.6e-29, (84.1% identity in 82 aa overlap). Also similar to ML0382, ML0639, ML0804 and ML2307 from M. leprae.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS903228903497+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0760|whiB2
VVPKALVAFEVESEPESSDQWQDRALCAQTDPEAFFPEKGGSTREAKKICLGCEVRHECLEYALAHDERFGIWGGLSERERRRLKRGVI
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