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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productprobable phosphomannomutase PmmA (PMM) (PHOSPHOMANNOSE MUTASE)
CommentsML0763, len: 468 aa. Probable pmmA, phosphomannomutase (EC 5.4.2.8), highly similar to O86374|Z95121|Rv3257c pmmA, probable phosphomannomutase from M. tuberculosis (465 aa), fasta scores: E(): 9.2e-162, (83.1% identity in 468 aa overlap); and CAD95377| from M. bovis (465 aa). Similar to several e.g. MANB_ECOLI|P24175 manB phosphomannomutase from Escherichia coli (456 aa), fasta scores: E(): 6.9e-58, (39.0% identity in 451 aa). Also similar to ML0366 and ML0706 from M. leprae. Contains Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS904676906082+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0763|pmmA
MSRPAAAVHRVVKAYDVRGLVGKEIDESLSADFGAAFARLMRAEGARQVVLGYDMRDSSPSLAAAFATGVTGQGVDVVRIGLSSTDQLYFAAGLLDCPGAMFTASHNPAAYNGIKLCLAGAKPVGADTGLAIIRDDVIAGIPPYPLSRGRPGTIADRDVLADYGVFLRSLVNTAGLRPLRVAVDAGNGMAGHTTPAVLGAIDSITLLPLYFELDGSFPNHEANPLDPANLVDLQAYVRDTGADIGLAFDGDADRCFVVDERGLSVSPSTVTSLVAARALKREIGATIIYNVITSRAVPELVSECGGTPLRSRVGHSYIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALYVLAALGEQQRPLSELAADYQRYESSGEINFTVADAPSCMDAVVEFFGSQIHSIDHLDGVTVDLGGGSWFNLRNSNTEPLLRLNVEGRSTEDVDVVVAQISAQIAAHISGPEAEP
      
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