Gene ML0803 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0803
Gene length1503 bp
IdentifierML0803
Location 952105 bp
Protein summary information
Molecular mass54104.7 Da
Isoelectric point6.31
Protein length501 amino acids
Structural information
PFAMPF02518, PF07568, PF08448
Orthologues
M. tuberculosisRv3220c
Cross-references
UniProtQ9CCH8
Gene OntologyPeptidyl-histidine phosphorylation, Signal transduction, Phosphorelay sensor kinase activity, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable two-component sensor kinase
CommentsML0803, len: 500 aa. Probable two-component sensor kinase, highly similar to Rv3220c|MTCY07D11.06|O05846|Z95120 Probable two component sensor kinase from M. tuberculosis (501 aa), fasta scores: E(): 5.1e-165, (81.8% identity in 501 aa), and CAD95338|Mb3246c from M. bovis (501 aa). Similar to others e.g. Q82IW5 Putative two-component system sensor kinase from Streptomyces avermitilis (501 aa), fasta scores: E(): 3.9e-78, (45.892% identity in 499 aa overlap). Contains Pfam match to entry PF00512 signal, Histidine kinase. SEEMS SIMILAR TO OTHER PROKARYOTIC SENSORY TRANSDUCTION HISTIDINE KINASES.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS952105953607+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0803|ML0803
MSTLGDLLAEHTVLPGNAVGHLHAVVGEWQLLADLSFADYLMWVSRDDGVLVCVAQCRPHTAPTVLQTDAVGSVASADMLPLVTEMFTSGAVQHEDAAGQQYSWLPFGRNVAASPVRYGDQVVAVLTQHQVELAARRRPGNLEIAYLACATDLLHMLAEGTFPDVGDVAVSHSTPRAGDGFIRLDRNGVVAFASPNALSAFHRMGLTAELQGRNLVKVTRPLLSDPFEAQEVAKHVQDLLDGGPSMRVEVNAGGATVLLRTLPLVVHGSSVGAAVLVRDVTEVKRRDRALISKDATIREIHHRVKNNLQTVAALLRLQARRMANAEGREALIESVRRVSSIALVHDALSMSVDEQVNLDEVIDRILPIMNDVASVDRPIRINRVGNLGMLDSDRATALIMVITELVQNAIEHAFDPASQEGFVAISAERSARWLDVVVHDDGRGLPQGFNLERSDSLGLQIVRTLVSSELDGSLGMRKAPNRGTDVVLRVPIGRRARLLL
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