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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE)
CommentsML0817, len: 395 aa. Probable moeB1, molybdopterin cofactor biosynthesis protein. Similar to Rv3206c|O05860|AL123456 M. tuberculosis moeB homologue (392 aa), Fasta scores: E(): 0, 86.4% identity in 391 aa overlap and to Rv3116|O05792|AL123456 M. tuberculosis moeB2 putative molybdopterin biosynthesis protein (389 aa), Fasta scores: E(): 0, 57.8% identity in 384 aa overlap. Similar to many e.g. Q9ZNW0|AF124160 Arabidopsis thaliana cnx5, molybdopterin synthase sulphurylase, (464 aa), Fasta scores: E(): 0, 34.5% identity in 406 aa overlap. Contains Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain. Contains Pfam match to entry PF00899 ThiF_family, ThiF family. BELONGS TO THE HesA /MoeB/ThiF FAMILY
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS965933967120+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0817|moeB1
MSTSSTSLPPLVEPAGQLSRDEVIRYSRHLIIPDIGVDGQMRLKSARVLVIGAGGLGAPVLLYLAAAGVGTIGIIDFDVVDESNLQRQIIHGVADVGRSKAQSARDSIVAINPLVQVRLHEFRLESSNVVNLFKQYDLIVDGTDNFATRYLINDAAVLAKKPYVWGSLYRFEGQVSVFWEDAPDGLGLNYRDLYLEPPPPGMVPSCAEGGVLGIVCASIASVMGTEAIKLITGIGAPLLGRLMIYNALEMSYRRIRIHKDPSRPKITELTDYQQFCGVVSDDAAQVATGSIVTPRELRELLDSGKKLALIDVREPVEWDIVHIDGAQLIPRSLINSGEGLAKLPQDRMSVLYCKTGVRSAETLATVKKAGFSDAVHLQGGIVAWAKQVQPDMVIY
      
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