Gene ML0826 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameglyS
Gene length1392 bp
IdentifierML0826
Location 978844 bp
Protein summary information
Molecular mass52957.6 Da
Isoelectric point5.39
Protein length464 amino acids
Structural information
PFAMPF00587, PF03129
Orthologs
M. tuberculosis H37RvRv2357c
M. lepromatosis Mx1-22AMLPM_0826
Cross-references
UniProtQ9CCG4
Gene OntologyAtp binding, Cytoplasm, Glycine-trna ligase activity, Glycyl-trna aminoacylation
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLYCYL-tRNA SYNTHETASE GLYS (GLYCINE--tRNA LIGASE) (GLYRS)
CommentsML0826, len: 463 aa. Probable glyS, glycyl-tRNA synthetase (EC 6.1.1.14). Similar to Rv2357c|MTCY27.23|MTCY98.26|SYG_MYCTU|O65932 Mycobacterium tuberculosis glycyl-tRNA synthetase glyS (463 aa) fasta scores: E(): 0, 90.2% identity in 459 aa and to SYG_THETH|P56206 Thermus aquaticus glycyl-tRNA synthetase glyS (505 aa) fasta scores: E(): 0, 43.6% identity in 512 aa. Contains Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II (G, H, P, S and T). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. BELONGS TO CLASS-II AMINOACYL-TRNA SYNTHETASE FAMILY.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS978844980235+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0826|glyS
VPCLVASVIDTVVNLAKRRGFVYPAGEIYGGTKSAWDYGPLGVEFKENIKRQWWRSVVTGREDVVGIDSSIILPRQVWVASGHLEIFHDPLVESLITHKRYRADHLIEAYEAKHGQSPCNGLADIRDPDTGEPGQWTEPREFNLMLKTYLGPIETEEGLHYLRPETAQGIFINFANVVTTARRKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTARDWHQYWIDTRMQWYVELGIDPQNLRLFEHPKDKLSHYSDRTVDIEYKFGFVGNPWGELEGVANRTDFDLSTHARYSGVDLSFYDQVNDTRYTPYVIEPAAGLTRSFMAFLIDAYTEDEAPNTRGGMDKRALLRLDPRLAPIKAAVLPLFRHVDLSPKARDLAAELRKCWNSEFDDAGAIGRRYRRQDEVGTPFCVTVDFESLDDNAVTVRERDAMTQERVAMTNVADYLAVRLKGS
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