Gene ML0833 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namednaG
Gene length1929 bp
IdentifierML0833
Location 988461 bp
Protein summary information
Molecular mass70761.0 Da
Isoelectric point5.67
Protein length643 amino acids
Structural information
PFAMPF01751, PF01807, PF08275, PF08278, PF10410
Orthologs
M. tuberculosis H37RvRv2343c
M. lepromatosis Mx1-22AMLPM_0833
Cross-references
UniProtQ9CCG2
Gene OntologyDna primase activity, Dna replication, synthesis of rna primer, Alpha dna polymerase:primase complex, GO:0006350, Zinc ion binding, Dna binding
Enzyme Classification2.7.7.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE DNA PRIMASE DNAG
CommentsML0833, len: 642 aa. Probable dnaG, DNA primase (EC 2.7.7.-). Similar to Rv2343c|PRIM_MYCTU|P95239 Mycobacterium tuberculosis DNA primase (639 aa) fasta scores: E(): 0, 80.4% identity in 642 aa, and to O52200|AF027507 Mycobacterium smegmatis primase dnaG (636 aa) fasta scores: E(): 0, 76.2% id in 642 aa. Contains Pfam match to entry PF01751 Toprim, Toprim domain. Contains Pfam match to entry PF01807 zf-CHC2, CHC2 zinc finger.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS988461990389+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0833|dnaG
MVGRIPDRDIAAIRERVCIEEVVGDYVQLRRAGADSLKGLCPFHNEKSPSFHVRPNHGHFHCFGCSEGGDVYAFIQKIEHVSFVEAVEMLADRIGHTINYFGTATSVQRDRGSRSRLIAANAAAAAFYAAALESDEAAPARQYLMERNFDANAARHFGCGFAPSGWDSLTKYLISKGFEFTELEAAGLSRQGRRGPMDRFHRRLLWPILTLAGEVIGFGARRLFDDDPMEAKYVNTPETLLYKKSSVMFGIDLAKRDIVKGHQAVVVEGYTDVMAMHLAGVTTAVASCGTAFGDEHLAMLRRLIMDDNWYRGELIFVFDGDAAGQAAALKAFDGDQQVAGKSFVAVAADGMDPCDLRLSSGDQALRDLVACRKPMFEFAIRSLIPDGMVLDDDPQAKVDALRRSVPLVARIRDYALRDEYARRLAGWTGWSDEGQVLARVREEANRRSVPERTRRRSVSVEQSPFMQPPGAPADQLAARPDPRDPTLWPQREALKSVLQYPVLAGPVFDTLTVESFTHPGYGAVRAAIDAAGGASAGITGAQWIDVVRQQTTSALIAGLINELGVESIQVDDEKLPRYIDGVLARLQEVWMGRQIAEVKSKLQRMSPIDQGDEYHELFGDLVAMEAYRRSLLEQASGDDMTA
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