Gene ML0844
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE NITRITE EXTRUSION PROTEIN 1 NARK (NITRITE FACILITATOR 1) |
| Comments | ML0844, len: 517 aa. Probable narK, nitrite extrusion protein, possibly member of major facilitator superfamily (MFS). Similar to Mycobacterium tuberculosis putative nitrite extrusion protein narK1 or Rv2329c or MTCY3G12.05 TR:P71883 (EMBL:Z79702) (515 aa) fasta scores: E(): 0, 69.3% identity in 488 aa and to Escherichia coli nitrite extrusion protein 2 narU SW:NARU_ECOLI (P37758; P77696) (462 aa) fasta scores: E(): 0, 36.6% identity in 459 aa. There is a frameshift near the C-terminus relative to the M. tuberculosis homologue. Previously sequenced as TR:O32974 (EMBL:Z98741). Contains hydrophobic, probable membrane-spanning regions. BELONGS TO THE NARK/NASA FAMILY OF TRANSPORTERS. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1002562 | 1004115 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0844|narK
MDQLVLLQAEESLYGPGRRSKTVPIDHRHSLKSSFFRLRLRRACRISHWDPEDQAAWEAGNKTIARLNLLWSVLTVHLGYSVWTLWPVMELFMPKDVYGFSAGDKFLLATTATLVGACLRVPYSLATALFGGRNWAIFSVMVLLIPTIATMVLLAHPGLPLWPYLACAALTGLGGGNFAASMTNANAFYPHRLKGAAFGLAGGAGNLGVSVIQVVGMLVIASVGDRKPYIVCGLYVVLLIIAGIGAMLFMNDIEHHRIGVNTIRPVLFVVVSTRDSWVLALLYLASFGSFIGFSFAFGQVLETNFVAGGQSTAQAALHAAELAFIGPTLAAVARFWGGRLADRLGGSRVTLVVFGAMVFAAGLLGVLGIIEGSRVCPIRGVMMASYFAGFITLFILSGLGNGSVYKMIPTIFEACSHSLGINDDECRDWSRVISGVVIGFVAEVGALGGVGIDLALRESYLNTGGVTAAFWIFMLCYAAAGVLTWKMYVCRPLPGNLHDEAANAFAASVGASRTHRG
Bibliography
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