Gene ML0857c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML0857c
Gene length753 bp
IdentifierML0857c
Location 1019693 bp
Protein summary information
Molecular mass26808.4 Da
Isoelectric point12.07
Protein length251 amino acids
Orthologs
M. tuberculosis H37RvRv2219
M. lepromatosis Mx1-22AMLPM_0857
Cross-references
UniProtQ7AQE8
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsML0857c, len: 250 aa. Probable conserved transmembrane protein. Similar to Mycobacterium tuberculosis hypothetical 26.9 kDa protein Rv2219 or MTCY190.30 SW:YM19_MYCTU (Q10405) (250 aa) fasta scores: E(): 0, 80.8% identity in 250 aa. Similar to Streptomyces coelicolor putative integral membrane protein SC3H12.04 TR:CAB90843 (EMBL:AL355740) (234 aa) fasta scores: E(): 1.2e-26, 39.6% identity in 230 aa and to Streptomyces coelicolor putative integral membrane protein SC5F7.05 TR:Q9S2P0 (EMBL:AL096872) (234 aa) fasta scores: E(): 1.2e-26, 39.6% identity in 230 aa. Previously sequenced as TR:O32963 (EMBL:Z98741). Contains hydrophobic, possible membrane-spanning regions.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10196931020445-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0857c|ML0857c
MAKPRNAAAHKAARAEAKAARKAASRQRRLQLWQAFTIQRTEDKRLIPYMIAAFSLMVSASVTAGVLVGGLTMITLILLGVVLGALVAFIIFGRRTQQSVYHKAEGQTGGAAWALDNLRGKWRVSPGVAANGHFDAVHRVIGRPGVIFVAEGSAARVKPLLAQEKKRTARLVGDVPIYDIIVGNGDGEVALVKLERHLARLPANISVKQVDILESRLAALGSRAGASLIPKGPLPNAGKMRGVQRTVRRK
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