Gene ML0865 in Mycobacterium leprae TN
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegcvT
Gene length1104 bp
IdentifierML0865
Location 1029024 bp
Protein summary information
Molecular mass38847.1 Da
Isoelectric point4.87
Protein length368 amino acids
Structural information
PFAMPF01571, PF08669
Orthologs
M. tuberculosis H37RvRv2211c
M. lepromatosis Mx1-22AMLPM_0865
Cross-references
UniProtO32955
Gene OntologyCytoplasm, Glycine decarboxylation via glycine cleavage system, Transaminase activity, Aminomethyltransferase activity
Enzyme Classification2.1.2.10
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable aminomethyltransferase GcvT (Glycine cleavage system T protein)
CommentsML0865, len: 367 aa. Probable gcvT, aminomethyltransferase (EC 2.1.2.10). Similar to Mycobacterium tuberculosis probable aminomethyltransferase gcvT or Rv2211c or MTCY190.22 SW:GCST_MYCTU (Q10376) (379 aa) fasta scores: E(): 0, 84.7% identity in 367 aa. Similar to many e.g. Escherichia coli aminomethyltransferase gcvT SW:GCST_ECOLI (P27248) (363 aa) fasta scores: E(): 0, 39.0% identity in 364 aa. Previously sequenced as TR:O32955 (EMBL:Z98741). Contains Pfam match to entry PF01571 GCV_T, Glycine cleavage T-protein (aminomethyl transferase). Belongs to the gcvT family.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10290241030127+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0865|gcvT
VTDAPELLKGPLEDRHRELGANFAEFGGWLMPVSYAGTVSEHSATRNAVGLFDVSHLGKALVRGPGAAQFVNSVLTNDLGRIRPGKAQYTLCCSESGGVIDDLIAYYVDDDEIFLVSNAANTAAVVDALQAVVPAGLTIINQHRSHAVLAVQGPRSTDVLGELGLPTGIDYMGYVDASYAGVPVRVCRTGYTGEQGYELLPPWESADVVFDALVAAVVDARGEPAGLGARDTLRTEMGYPLYGHELSLDISPLQARCGWAIGWKKDAFLGRDALLAEKAAGPRRLLRGLRMAGRGVLRPGLTVCAGDIPIGVTTSGTFSPTLQVGVALALIDSEAAVQDGQQIIVDVRGRAVECEVVRPPFIEVKTR
Bibliography
No article yet recorded