Gene ML0887c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadD15
Gene length1803 bp
IdentifierML0887c
Location 1053286 bp
Protein summary information
Molecular mass64462.4 Da
Isoelectric point6.21
Protein length601 amino acids
Structural information
PFAMPF00501
Orthologs
M. tuberculosis H37RvRv2187
M. lepromatosis Mx1-22AMLPM_0887
Cross-references
UniProtQ9CCE6
Gene OntologyMetabolic process, Ligase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)
CommentsML0887c, len: 600 aa. Probable fadD15, long-chain-fatty-acid-CoA ligase (EC 6.2.1.3). Similar to Mycobacterium tuberculosis putative long-chain-fatty-acid-CoA ligase, fadD15, TR:O53521 (EMBL:AL021957) (600 aa), Fasta scores: E(): 0, 80.3% identity in 600 aa overlap. The C-terminus of the predicted product of this CDS is identical to the previously sequenced Mycobacterium leprae putative long-chain- fatty-acid-CoA ligase TR:O69578 (EMBL:AL022602) (351 aa), Fasta scores: E(): 0, 100.0% identity in 351 aa overlap. Also similar to Haemophilus influenzae putative long-chain-fatty-acid-CoA ligase (EC 6.2.1.3) SW:LCFH_HAEIN (SW:P44446) (607 aa), Fasta scores: E(): 0, 30.3% identity in 587 aa overlap. Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme. Contains PS00455 Putative AMP-binding domain signature.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS10532861055088-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0887c|fadD15
VREFSVPTRFSVGEHDNIAAVVFEHERDDPNLVIYQRQIDGVWTDVTCAEAASQIRSAALGLIALGMQAGDRVSIFSATCFEWAILDLAILSVGAVTVPIYETSSAKQVRWILQDSDAVLVFAETDAHATMVNQLAGELPALRQVLQINSAGATALDQLAEAGASVDVAQLANRLKTLRAQDPATLIYTSGTTGRPKGCQLTHSNLLYEVRGAKECLPTLLQPGQRLLVFLPLAHVLARALTLSAFTYKMTVGFTSDIKNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAANEGKSRIFAMAAQTAVEWSEASHRGGPGLLLRARHAVFDRLVYRKLRAALGGDCHASVSGGAPLGARLGHFYRGVGLTIHEGYGLTETSAAITLNQAGNVKVGTVGNLLPGNSMRIADDGELLVRGNVVFSGYWHNEQGTIEAFTEGWFKTGDLGAIDEDGFLTITGRKKEIIVTAGGKNVAPALLEDQLRAHPLISQALVVGDAKPFVGALITIDPEAFNGWKQRNSKAADAAIGDLTTDPDLVAEVDAAVKQANLSVSHAESIRKFRILPVDFTEQTGELTPTMKVKRNVVAQKFASDIEAIYEKD
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