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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GTP-BINDING PROTEIN HFLX
CommentsML0997, len: 488 aa. Probable hflX, GTP-binding protein (EC 3.1.5.-). Identical to the previously sequenced Mycobacterium leprae HflX protein TR:Q49843 (EMBL:U00019) (518 aa), Fasta scores: E(): 0, 100.0% identity in 488 aa overlap. Also highly similar to Mycobacterium tuberculosis hypothetical protein Rv2725c TR:O33230 (EMBLZ98209:) (495 aa), Fasta scores: E(): 0, 84.5% identity in 485 aa overlap and Escherichia coli GTP-binding protein HflX, located within the hflA (high frequency of lysogenization) locus governing lysis and lysogeny of bacteriophage lambda, SW:HFLX_ECOLI (P25519) (426 aa), Fasta scores: E(): 0, 38.3% identity in 428 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS11652731166739+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML0997|hflX
MKYPDSSDRGSADFPDLWDSSDSVPSTGELALHDRLALRRIAGLSTELADVSEVEYRQLRLERVVLVGVWTEGSAADNQASMAELATLAETAGSQVLEGLIQRRDRPDPSTYIGSGKAAELREVVLATGADTVICDGELSPAQLTALEKAVKVKVIDRTALILDIFAQHATSREGKAQVLLAQMAYMLPRLRGWGESMSRQVGGRAGGSGGGVGLRGPGETKIETDRRRIRERMAKLRRDIGAMKQARDTQRSRRLHSDIPSIAIVGYTNAGKSSVLNALTGAWVLVQDALFVTLEPTTRHAEFDNGQPFVFTDTVGFVRHLPTQLVEAFRSTLEEVVDADLLLHVVDGSDANPLAQINAVRQVIFEVISDHQDGGVEVPHELLVVNKIDAASALMLAKLRHGLPGAVFISARTGDGIDVLRRRIAELVVATDTAVDVVIPYDRGDLVARLHANGRVQQAEHNSNGTRIKARVPVALAACLQEFSADR
      
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