Gene ML1005 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1005
Gene length465 bp
IdentifierML1005
Location 1176667 bp
Protein summary information
Molecular mass17325.5 Da
Isoelectric point8.51
Protein length155 amino acids
Structural information
PFAMPF03477
Orthologs
M. tuberculosis H37RvRv2718c
M. lepromatosis Mx1-22AMLPM_1005
Cross-references
UniProtQ49844
Gene OntologyDna binding, Regulation of transcription, dna-dependent, GO:0006350, Transcription repressor activity, Zinc ion binding, Atp binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productconserved hypothetical protein
CommentsML1005, len: 154 aa. Conserved hypothetical protein. Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49844 (EMBL:U00019) (154 aa), Fasta scores: E(): 0, 100.0% identity in 154 aa overlap. Also highly similar to a number of other proteins of unknown function e.g. Mycobacterium tuberculosis Rv2718c TR:O07217 (EMBL:Z96072) (154 aa), Fasta scores: E(): 0, 92.7% identity in 151 aa overlap and Escherichia coli SW:YBAD_ECOLI (P25538) (149 aa), Fasta scores: E(): 9.7e-21, 45.6% identity in 147 aa overlap. Belongs to the UPF0168 family.
Functional categoryConserved hypotheticals, Regulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS11766671177131+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1005|ML1005
MHCPFCRHSDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVVAVVKRSGVTEPFSRGKVIRGVRRACQGRQVDDDALNLLAQQVEDTVRAAGLPEVPSHEVGLAILGPLRELDEVAYLRFASVYRSFSSADDFEREIEALRAHRRVSTSR
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