Gene ML1066 in Mycobacterium leprae TN
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametagA
Gene length579 bp
IdentifierML1066
Location 1230988 bp
Protein summary information
Molecular mass21633.5 Da
Isoelectric point7.97
Protein length193 amino acids
Structural information
PFAMPF03352
Orthologs
M. tuberculosis H37RvRv1210
M. lepromatosis Mx1-22AMLPM_1066
Cross-references
UniProtQ49957
Gene OntologyBase-excision repair, Dna-3-methyladenine glycosylase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE DNA-3-METHYLADENINE GLYCOSYLASE I TAGA (TAG I) (3-methyladenine-DNA glycosylase I, constitutive) (DNA-3-methyladenine glycosidase I )
CommentsML1066, len: 192 aa. Probable tagA, DNA-3-methyladenine glycosidase I (EC 3.2.2.20). Identical to the previously sequenced Mycobacterium leprae TR:Q49957 (EMBL:U15180) (192 aa), Fasta scores: E(): 0, 99.5% identity in 192 aa overlap. Also highly similar to DNA-3-methyladenine glycosidases from Mycobacterium tuberculosis Rv1210 TR:O05311 (EMBL:Z93777) (204 aa), Fasta scores: E(): 0, 80.2% identity in 192 aa overlap and Escherichia coli SW:3MG1_ECOLI (P05100) (187 aa), Fasta scores: E(): 1.8e-27, 43.8% identity in 185 aa overlap.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12309881231566+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1066|tagA
VSDDGLVRCGWADVRSGLHWQLYRNYHDQEWGSPVRCGVALFERMSLEAFQSGLSWLLILRKRENFRRAFSGFDIEEVARYTHADVQRLLFDDGIVRNRVKIEATIANARAAAELGSAADLSELLWSFAPQPRSRPADGSEIPSTSAEAKAMARELKRRGFRFVGPTTAYALMQATGMVDDHICTCWVPPTR
Bibliography
No article yet recorded