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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB
CommentsML1088, len: 287 aa. Probable sugB, sugar-transport integral membrane protein ABC transporter. Previously sequenced Mycobacterium leprae MalG TR:Q49977 (EMBL:U15180) (296 aa), Fasta scores: E(): 0, 100.0% identity in 287 aa overlap. Also highly similar to many putative membrane transport proteins including: Mycobacterium tuberculosis probable sugar transport protein Rv1237 TR:O50453 (EMBL:AL021006) (274 aa), Fasta scores: E(): 0, 89.4% identity in 274 aa overlap and Thermococcus litoralis inner membrane protein MalG TR:O51925 (EMBL:AF012836) (278 aa), Fasta scores: E(): 4.1e-31, 35.9% identity in 270 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS12506671251530+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1088|sugB
MGIEKVKVTAGVRVGARRATIWVIIDTFVVGYALLPVLWILSLSLKPASTVKDGKLIPSLVTFDNYRGIFRSDLFSSALINSIGIGLTTTVIAVMFGAMAAYAIARLAFPGKRLLVGTTLLVTMFPAISLVTPLFNIERRVGLFDTWAGLILPYITFALPLAIYTLSAFFAEIPWDLEKAAKMDGATSGQAFRKVIVPLAAPGLVTAAILVFIFAWNDLLLALSLTSTKAAITAPVAITNFTGSSQFEEPTGSIAAGAIVITAPIIVFVWIFQRRIVAGLTSGAVKG
      
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