Gene ML1132 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namerho
Gene length1833 bp
IdentifierML1132
Location 1323334 bp
Protein summary information
Molecular mass66070.5 Da
Isoelectric point5.15
Protein length611 amino acids
Structural information
PFAMPF00006, PF07497, PF07498
Orthologues
M. tuberculosisRv1297
Cross-references
UniProtP45835
Gene OntologyAtp synthesis coupled proton transport, Rna binding, Helicase activity, Hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, Proton-transporting two-sector atpase complex, catalytic domain, Regulation of transcription, dna-dependent, Dna-dependent transcription, termination, Transcription termination factor activity, Atp binding
Enzyme Classification3.6.1.-
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTION TERMINATION FACTOR RHO HOMOLOG
CommentsML1132, len: 610 aa. Probable transcription termination factor rho homolog. Identical to the previously sequenced Mycobacterium leprae transcription termination factor Rho SW:RHO_MYCLE (P45835) (610 aa), Fasta scores: E(): 0, 99.8% identity in 610 aa overlap. Also highly similar to many other transcriptional terminators including: Mycobacterium tuberculosis Rv1297 SW:RHO_MYCTU (Q10607) (602 aa), Fasta scores: E(): 0, 81.5% identity in 616 aa overlap and Micrococcus luteus SW:RHO_MICLU (P52154) (690 aa), Fasta scores: E(): 0, 66.0% identity in 467 aa overlap. Contains Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS13233341325166+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1132|rho
VTETDLITVGENTDDTELTNAVTTDTPDVKATAATVSLGSLSTMVLPELRALANQAGVKGTSGMRKSELIAAIEECRGQANGTSVNDGPSRDHGGSATAISTEALAAQEEQNYAIVEVSRRERRGASREADVTAGTSTAEATESDCQGTADDDTRTLQGGQSDTKTEERGPDVGNDQGVEQQSSSLQPRGDDDGEGRQGRRGRRFRDRDRRRRGERSGDGAEAELRQDDVVQPVAGILDVLDNYAFVRTSGYLAGPHDVYVSMSMVRKNGLRRGDAVTGAVRVPREGEQGHQRQKFNPLVRLDSINGGSVEDAKKRPEFGKLTPLYPNQRLRLETTPDRLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITRNNLECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDMVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLSPDEFGIVHKLRRVLSGLDSHQAIDLLMSQLRKTKTNYEFLVQVSKTTPGSMDDD
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