Gene ML1254 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1254
Gene length648 bp
IdentifierML1254
Location 1498709 bp
Protein summary information
Molecular mass23867.5 Da
Isoelectric point10.58
Protein length216 amino acids
Structural information
PFAMPF01844
Orthologs
M. tuberculosis H37RvRv2469c
M. lepromatosis Mx1-22AMLPM_1254
Cross-references
UniProtQ7AQ78
Gene OntologyNucleic acid binding, Endonuclease activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productconserved hypothetical protein
CommentsML1254, len: 215 aa. Conserved hypothetical protein. Highly similar to several proteins of unknown function including: Mycobacterium tuberculosis Rv2469c TR:O53196 (EMBL:AL021246) (222 aa), Fasta scores: E(): 0, 77.9% identity in 222 aa overlap and Streptomyces coelicolor TR:CAB71830 (EMBL:AL138662) (178 aa), Fasta scores: E(): 0, 52.8% identity in 161 aa overlap. Contains Pfam match to entry PF01844 HNH, HNH endonuclease.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS14987091499356+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1254|ML1254
MVQRKNRRSHRSSGAAANLIRAANPSSLHNVDIHPSTCYESGSIWNRRRVLLLNSTYEPLTALPTRRAIIMVICGKADVVHVDPAGPVVHSATRSITVPSVIQLRSYVRVPYRARVPMTRAALMHRDRFCCAYCGAKADTVDHVVPRSRGGDHSWENCVACCSTCNHRKGDKLLTELGWVLRRTPVLPTGQHWRLLSTVKELDPAWARYLGGGAA
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