Gene ML1267 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namechaA
Gene length1095 bp
IdentifierML1267
Location 1510443 bp
Protein summary information
Molecular mass37898.7 Da
Isoelectric point9.04
Protein length365 amino acids
Structural information
PFAMPF01699
Orthologs
M. tuberculosis H37RvRv1607
M. lepromatosis Mx1-22AMLPM_1267
Cross-references
UniProtQ7AQ77
Gene OntologyIntegral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable ionic transporter integral membrane protein ChaA
CommentsML1267, len: 364 aa. Probable chaA, ionic transporter integral membrane protein, putative calcium/proton antiporter. Highly similar to many antiporters e.g. Mycobacterium tuberculosis Rv1607 TR:O53910 (EMBL:AL022001) (360 aa), Fasta scores: E(): 0, 77.7% identity in 364 aa overlap and Escherichia coli SW:CHAA_ECOLI (P31801) (366 aa), Fasta scores: E(): 0, 36.5% identity in 356 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15104431511537+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1267|chaA
MLKRIAWTALVPLFALAVLALTWGREIGPVVTALQAALLTGAVLAAVHHAEVVAHRVGEPFGSLVLAAAVTVIEVALIVTLMASGENESWTLARDTAFAALMITTNGIAGFSLLLGSRRYGVTLFNAHGSGAALATLTTLATLSLVLPTFTTSHRGNEFSPGQLAFAAVASLGLYLLFVFTQTIRHRDFFLPVAQKGQKGLFEEDESHADPPSARSALISLALLLVALIAVVGLAELQSSAIEHLVTAVGFPQPFVGVVIATLVLLPETLAAVRAARRGRIQTSLNLAYGSAMASIGLTIPAIALASIWLTGPLILGLGATQLVLLALTVVISVLTVVPGRATRLQGEVHLVLLAAFVFLAIIP
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