Gene ML1288 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1288
Gene length1404 bp
IdentifierML1288
Location 1536153 bp
Protein summary information
Molecular mass50198.0 Da
Isoelectric point4.6
Protein length468 amino acids
Structural information
PFAMPF01546, PF07687
Orthologs
M. tuberculosis H37RvRv2141c
M. lepromatosis Mx1-22AMLPM_1288
Cross-references
UniProtQ9CC46
Gene OntologyProtein dimerization activity, Proteolysis, Zinc ion binding, Metallopeptidase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productpossible peptidase
CommentsML1288, len: 467 aa. Possible peptidase. Similar to several members of the ARGE/DAPE/ACY1 protein family including: Mycobacterium tuberculosis Rv2141c, TR:O06234 (EMBL:Z95388) (448 aa), Fasta scores: E(): 0, 83.9% identity in 448 aa overlap and Streptomyces coelicolor putative aminoacylase TR:Q9ZBI7 (EMBL:AL035161) (443 aa), Fasta scores: E(): 0, 47.6% identity in 433 aa overlap). Contains Pfam match to entry PF01546 Peptidase_M20, Peptidase family M20/M25/M40. Contains PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15361531537556+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1288|ML1288
VQKTKVLRSLVVAVVGKVTVTVETDVLVNPSDDVVEVVSRLIRFDTTNTGDPETTRGEAECAQWVASQLAEVGYQPEYLESGAPGRGNVFARLAGEDSSRGALLIHGHLDVVPAETAEWSVHPFSGAVEGGQVWGRGAIDMKDMVGMMIVVARQLKQAGIAPPRDLVFAFVADEEHGGSYGSQWLVDNRPDLFDGVTEAIGEVGGFSLTVPCRNGGERRLYLIETAEKGMQWMRLTARGRAGHGSMVHNQNAVTAVAEAVARLGRHQFPLVTTDTVVQFLAAISEETGLEFDIGSPDLEGAIEKLGPMARMLKAVLYDTANPTVLKAGYKVNVVPATAEAMVDCRILPGRQAAFEAAIDELIGPDVTREWIKDLPPYETAFDGDLVDAMNAAVLAVDPDGRTVPYMASGGTDAKAFARLGIRCFGFTPLRLPPELDFTALFHGVDERVSIDALKFGIDVLAHFLTHC
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