Gene ML1321 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepup
Gene length192 bp
IdentifierML1321
Location 1575497 bp
Protein summary information
Molecular mass7067.4 Da
Isoelectric point3.81
Protein length64 amino acids
Structural information
PFAMPF05639
Orthologues
M. tuberculosisRv2111c
Cross-references
UniProtQ9ZBE0
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productconserved hypothetical protein
CommentsML1321, len: 63 aa. Conserved hypothetical protein. Highly similar to many proteins of undefined function found upstream of bacterial proteasome beta subunits including: Mycobacterium smegmatis TR:O30517 (EMBL:AF009645) (64 aa), Fasta scores: E(): 6.2e-18, 82.8% identity in 64 aa overlap, Rhodococcus sp. TR:Q53082 (EMBL:U26422) (64 aa), Fasta scores: E(): 6.7e-17, 82.8% identity in 64 aa overlap and Mycobacterium tuberculosis Rv2111c TR:O33246 (EMBL:Z97559) (64 aa), Fasta scores: E(): 7.9e-19, 87.5% identity in 64 aa overlap. Note the high number of the amino acids Glu, Asp and Gly. Contains a possible coiled-coil region.
Functional categoryConserved hypotheticals, Intermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15754971575688+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1321|pup
MAQEQTRRGGGGDDDEFTSSTSVGQERREKLTEETDDLLDEIDDVLEENAEDFVRAYVQKGGQ
Bibliography
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