Gene ML1323 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameprcA
Gene length798 bp
IdentifierML1323
Location 1576557 bp
Protein summary information
Molecular mass28677.0 Da
Isoelectric point7.49
Protein length266 amino acids
Structural information
PFAMPF00227
Orthologs
M. tuberculosis H37RvRv2109c
M. lepromatosis Mx1-22AMLPM_1323
Cross-references
UniProtQ9S375
Gene OntologyProteasome core complex, Threonine-type endopeptidase activity, Ubiquitin-dependent protein catabolic process, Cytosol
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productprobable proteasome (alpha subunit) PrcA
CommentsML1323, len: 265 aa. Probable prcA, proteasome (alpha subunit 0 (EC 3.4.25.1). Highly similar to many proposed 20S proteasome alpha subunits including: Rhodococcus sp. TR:Q53080 (EMBL:U26421) (259 aa), Fasta scores: E(): 0, 65.5% identity in 255 aa overlap and Mycobacterium tuberculosis Rv2109c TR:O33244 (EMBL:Z97559) (248 aa), Fasta scores: E(): 0, 91.8% identity in 244 aa overlap.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS15765571577354+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1323|prcA
MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDEPHFMVMGGTTESIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQPTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSKGSKGAQNPKGARDSKNSKSYGESTD
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