Gene ML1351
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE 3-METHYLADENINE DNA GLYCOSYLASE MPG |
| Comments | ML1351, len: 214 aa. Possible mpg, 3-methylpurine DNA glycosylase (EC 3.2.2.-). Similar to several DNA-3-methyladenine glycosylases from both Prokaryotes and Eukaryotes e.g. Bacillus subtilis SW:3MGH_BACSU (P94378) (196 aa), Fasta scores: E(): 7.7e-13, 38.4% identity in 185 aa overlap and Arabidopsis thaliana SW:3MG_ARATH (Q39147) (254 aa), Fasta scores: E(): 1.1e-11, 32.0% identity in 194 aa overlap. Also highly similar to Mycobacterium tuberculosis Rv1688 putative 3-methyladenine DNA glycosylase SW:3MGH_MYCTU (O33190) (203 aa), Fasta scores: E(): 0, 78.3% identity in 203 aa overlap. Note codon 12 may offer an alternative translational start site. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1611524 | 1612168 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1351|mpg
LRSPRRCKICAVSADQLVVDPVVAAHRLLGATITGRGVCAIVVEVEAYGGVPDGPWPDAAAHSYHGRNDRNAVMFGPPGRLYTYCSHGIHVCANVSCGPDGTAAAVLIRAGALENGADVARSRRGASVRTVALARGPGNLCSALGITMDDNGIDVFAADSPVTLVLNEAQEAMSGPRVGISHAADRPWRLWLPGRPEVSTYRRSPRAPAPGASD
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