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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE INTEGRASE/RECOMBINASE
CommentsML1365, len: 316 aa. Probable integrase/recombinase. Highly similar to several including: Escherichia coli integrase/recombinase XerD which is involved in site specific recombination, SW:XERD_ECOLI (P21891) (298 aa), Fasta scores: E(): 5.7e-29, 40.3% identity in 308 aa overlap. Also similar to several other Mycobacterium tuberculosis integrase/recombinases e.g. Rv1701 TR:O33200 (EMBL:Z98268) (311 aa), Fasta scores: E(): 0, 85.9% identity in 311 aa overlap and Rv2894c SW:YS94_MYCTU (Q10815) (298 aa), Fasta scores: E(): 0, 42.9% identity in 312 aa overlap. Also similar to ML1365 from M. leprae. Contains Pfam match to entry PF00589 Phage_integrase, 'Phage' integrase family.
Functional categoryInsertion seqs and phages
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16265421627492+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium leprae TN|ML1365|ML1365
VTTAALQTQLQGYLDYLIIERSIAANTLSSYRRDLIRYSKHLSDRGIEDLAKVGEHDVSEFLVALRRGDPDSGVAALSAVSAARALIAVRGLHRFAVAEGLVDLDVARAVRPPTPGRRLPKSLTVDEVLALLESVGGESRADGPLVLRNRALLELLYSTGSRISEAVGLDVDDVDTQARTVLLQGKGGKQRLVPVGRPAVQALDAYLVRGRSDLARRGPGMLATPAIFLNARGGRLSRQSAWQVLQDAAEHAGITSGVSPHMLRHSFATHLLEGGADIRVVQELMGHASVTTTQIYTLVTVQALREVWAGAHPRAK
      
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