Gene ML1411 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameargR
Gene length504 bp
IdentifierML1411
Location 1693104 bp
Protein summary information
Molecular mass17120.2 Da
Isoelectric point4.61
Protein length168 amino acids
Structural information
PFAMPF01316, PF02863
Orthologs
M. tuberculosis H37RvRv1657
M. lepromatosis Mx1-22AMLPM_1411
Cross-references
UniProtP57992
Gene OntologyCytoplasm, Regulation of transcription, dna-dependent, GO:0006350, Sequence-specific dna binding transcription factor activity, Arginine biosynthetic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable Arginine repressor ArgR (AHRC)
CommentsML1411, len: 167 aa. Probable argR, Arginine repressor. Highly similar to many ArgR orthologues (which regulate the arginine biosynthetic genes) including: Bacillus stearothermophilus SW:ARGR_BACST (O31408) (149 aa), Fasta scores: E(): 2.3e-10, 33.8% identity in 154 aa overlap and Mycobacterium tuberculosis Rv1657 SW:ARGR_MYCTU (P94992) (170 aa), Fasta scores: E(): 0, 79.7% identity in 158 aa overlap. Belongs to the argR family.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS16931041693607+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1411|argR
MTHGASKTTPETTRAGRQARIVAILSSTSVRSQSELATLLADDGIDVTQATLSRDLEELGAVKLRGADGGVGVYVVPEDGSPVRGVSGGTARLSRLLSELLVSADSSANLAVLRTPPGAADYLASAIDRAALPYVVGTIAGDDTVFVAAREPMTGSELATVLESLNR
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