Gene ML1425c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1425c
Gene length852 bp
IdentifierML1425c
Location 1712643 bp
Protein summary information
Molecular mass32025.1 Da
Isoelectric point9.72
Protein length284 amino acids
Structural information
PFAMPF00528
Orthologues
M. tuberculosisRv2039c
Cross-references
UniProtQ7AQ53
Gene OntologyPlasma membrane, Transport, Transporter activity, Integral to membrane
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductProbable sugar-transport integral membrane protein ABC transporter
CommentsML1425c, len: 283 aa. Probable sugar-transport integral membrane protein ABC transporter. Highly similar to many putative ABC_transport proteins e.g. Mycobacterium tuberculosis sugar transport protein Rv2039c TR:O53483 (EMBL:AL021899) (280 aa), Fasta scores: E(): 0, 79.2% identity in 283 aa overlap. Also similar to ML2039c from M. leprae. Contains multiple possible membrane spanning hydrophobic domains. Contains Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component. Contains PS00402 Binding-protein-dependent transport systems inner membrane comp sign.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17126431713494-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1425c|ML1425c
VGLAERLNHIVKRSVLRAVVVYIALTGIAWCALFPIVWALSGSLKKEGEIREPTLLPAHPQWSNYTEVFDLIPFWRMFFNTVLYAGYVTVGQVFFCSLAGYAFARLQFRGRDALFVLYLGTLMMPLTVTIIPQFILMRVLGWTDTPWAMIVPGLFGSAFGTYLMRQFFRTLPSDLEEAAILDGCSPWQIYWRVLLPHAKPAVGVLAVLTWVNVWNDFLWPLLMIQRNSLATLTLGLVRMRGEYGTCWPVIMATSMLIILPLVIIYTIAQRAFVRGITVTRIGG
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