Gene ML1448
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE RNA POLYMERASE SIGMA FACTOR, ECF SUBFAMILY, SIGC |
| Comments | ML1448, len: 184 aa. Probable sigC, RNA polymerase sigma factor, ECF subfamily. Similar to many ECF-subfamily RNA polymerase sigma factors including: Bacillus subtilis SigX SW:SIGX_BACSU (P35165) (194 aa), Fasta scores: E(): 1.3e-07, 32.0% identity in 128 aa overlap and Mycobacterium tuberculosis Rv2069 SW:RPSC_MYCTU (Q10679) (185 aa), Fasta scores: E(): 0, 81.2% identity in 181 aa overlap. Also similar to ML1956c a possible pseudogene similar to M. tuberculosis sigC. Contains a putative helix-turn-helix motif situated between residues 156..177 (+2.77 SD). Contains a probable helix-turn-helix motif at aa 146-167 (Score 1052, SD +2.77) Contains Pfam match to entry PF00776 Sigma70_ECF, Sigma-70 factor (ECF subfamily). Contains PS01063 Sigma-70 factors ECF subfamily signature. Belongs to ECF subfamily. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1740908 | 1741462 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1448|sigC
MIASSGDEAVTDLALAAARGSKRALEAFIKATQQDVWRFVAYLSDVGNADDLTQETFLRAIGAIERFSGHSSGRTWLLAIARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARGFEDLVEVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADTEHNHLTG
Bibliography
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