Gene ML1454c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namenadD
Gene length645 bp
IdentifierML1454c
Location 1747951 bp
Protein summary information
Molecular mass23699.7 Da
Isoelectric point5.51
Protein length215 amino acids
Structural information
PFAMPF01467
Orthologs
M. tuberculosis H37RvRv2421c
M. lepromatosis Mx1-22AMLPM_1454
Cross-references
UniProtQ9CBZ8
Gene OntologyNad biosynthetic process, Nicotinate-nucleotide adenylyltransferase activity, Atp binding
Enzyme Classification2.7.7.18
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE) (NAMN ADENYLYLTRANSFERASE)
CommentsML1454c, len: 214 aa. Probable nadD, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18). Similar to several e.g. Mycobacterium tuberculosis Rv2421c TR:O86328 (EMBL:Z81368) (211 aa), Fasta scores: E(): 0, 80.2% identity in 212 aa overlap.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS17479511748595-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1454c|nadD
MGGTFDPIHYGHLVAASEVAHMFELDEVMFVPSGQPWQKGRHVSAAEDRYLMTVIATASNPRFSVSRVDIDRTGPTYTRDTVHDLHALNPDSELYFITGADALASILSWQGWDELFDLARFVGVSRPGYELGQEHITGVMGELPADALTLVEIPALAISSTDCRQRVEQRQPLWYLMPDGVVQYVFKRRLYRGPHGVAGTGRLTTPSLVVGNNT
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