Gene ML1519c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) |
| Comments | ML1519c, len: 266 aa. Probable thyA, thymidylate synthase (EC 2.1.1.45). Highly similar to many thymidylate synthases involved in deoxyribonucleotide biosynthesis including: Escherichia coli SW:TYSY_ECOLI (P00470) (264 aa), Fasta scores: E(): 0, 66.3% identity in 261 aa overlap and Mycobacterium tuberculosis Rv2764c SW:TYSY_MYCTU (O33306) (263 aa), Fasta scores: E(): 0, 85.5% identity in 262 aa overlap. Contains Pfam match to entry PF00303 thymidylat_synt, Thymidylate synthase. Contains PS00091 Thymidylate synthase active site. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1833030 | 1833830 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1519c|thyA
VLIATPYEDLLRLVLDCGVAKMDRTGTGTRSLFGQQLRYDLSVGFPLVTTKKVHFKSVVYELLWFLRGDSNVAWLHEHGVNIWDEWASSTGDLGPIYGVQWRSWPTSSGDYIDQISTALDLLRTEPDSRRIIVSAWNVGEIPQMALPPCHAFFQFYVAQGRLSCQLYQRSADMFLGVPFNIASYALLTHMMAAQSGLLVGEFVWTGGDCHIYDNHVEQVQLQLSREPRAYPELFLAQRDSIFDYVYEDVVVTNYDPHPAIKAPVAI
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