Gene ML1532 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameald
Gene length1116 bp
IdentifierML1532
Location 1846971 bp
Protein summary information
Molecular mass38845.2 Da
Isoelectric point5.72
Protein length372 amino acids
Structural information
PFAMPF01262, PF05222
Orthologs
M. tuberculosis H37RvRv2780
M. lepromatosis Mx1-22AMLPM_1532
Cross-references
UniProtQ9CBV6
Gene OntologyBinding, Electron carrier activity, Metabolic process, Alanine dehydrogenase activity
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductSECRETED L-ALANINE DEHYDROGENASE ALD (40 KDA ANTIGEN) (TB43)
CommentsML1532, len: 371 aa. Probable ald, secreted L-alanine dehydrogenase (EC 1.4.1.1). Highly similar to many alanine dehydrogenases including: Bacillus sphaericus SW:DHA_BACSH (P175566) (372 aa), Fasta scores: E(): 0, 53.4% identity in 365 aa overlap and Mycobacterium tuberculosis Rv2780 SW:DHA_MYCTU (P30234) (371 aa), Fasta scores: E(): 0, 85.4% identity in 371 aa overlap. Contains Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase. Contains PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. Contains PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18469711848086+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1532|ald
MRVGIPTETKNNEFRVAITPAGVAALTHRGHEVLVQAGAGEGSAIADAEFKAAGAQLISTPEQVWTEVDLLLKVKEPMPAEYVHLRHGQILFTYLHLAASRPCTDALLASGTTSIAYETVQTADGALPLLAPMSEVAGRLSAQVGAYHLMRTHRGCGVLMGGVPGVEPADVVVIGGGTAGYNAARIANGMGATVTVFDVNINRLRELDAEFGGRLRTRYSSAYDLEGAVKHADLVIGAVLVPGAKAPRLISNSLVAHMKPGAVLVDIAIDQGGCFEDSQPTTHDQPTFAVHDTLFYCVANMPSAVPKTSTFALTNATMPYILKLADQGWQEACQSDPALAKGLSTHNGALLSEQVATDLGLAFTEPASVLA
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