Gene ML1547c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepptT
Gene length684 bp
IdentifierML1547c
Location 1871964 bp
Protein summary information
Molecular mass24867.7 Da
Isoelectric point6.28
Protein length228 amino acids
Structural information
PFAMPF01648
Orthologs
M. tuberculosis H37RvRv2794c
M. lepromatosis Mx1-22AMLPM_1547
Cross-references
UniProtQ7AQ45
Gene OntologyEnterobactin synthetase complex, Holo-[acyl-carrier-protein] synthase activity, Macromolecule biosynthetic process, Magnesium ion binding, Enterobactin biosynthetic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productprobable phosphopantetheinyl transferase, by homology with phosphopantetheinyl transferase pptT(Rv2794c) from M. tuberculosis H37Rv
CommentsML1547c, len: 227 aa. Highly similar to phosphopantetheinyl transferase pptT from Mycobacterium tuberculosis Rv2794c (227 aa), Fasta scores: E(): 0, 79.7% identity in 227 aa overlap. Weakly similar to a number of proteins essential for the production of iron chelators e.g. Escherichia coli enterobactin synthetase component D SW:ENTD_ECOLI (P19925) (209 aa), Fasta scores: E(): 0.002, 29.4% identity in 177 aa overlap. Also similar to Streptomyces sp. L-proline 3-hydroxylase TR:O24813 (EMBL:AB007189) (208 aa), Fasta scores: E(): 0, 50.7% identity in 209 aa overlap
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18719641872647-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1547c|pptT
MTVSMLVSSVLPDYASQDLEYAELYSDPPGLTPLPEEELLIAKSVAKRRNEFITARYCARIALGRLRVPPVPILKGDKGEPCWPDGVVGSLTHCSGYRGAVVGRSAAVRSVGIDAEPHEMLPNGVLDVISLPEERSEMRRKLPSVLYWDRILFCAKEATYKAWFPLTKRWLGFEDAHITFDVDNLGSSGGFVSRILVDGSALSGPPLTVLTGRWSVDRGLVLTAIVL
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