Gene ML1573c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameML1573c
Gene length750 bp
IdentifierML1573c
Location 1898989 bp
Protein summary information
Molecular mass26637.2 Da
Isoelectric point4.67
Protein length250 amino acids
Structural information
PFAMPF07722
Orthologs
M. tuberculosis H37RvRv2859c
M. lepromatosis Mx1-22AMLPM_1573
Cross-references
UniProtQ9CBU9
Gene OntologyHydrolase activity, Transferase activity, Glutamine metabolic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
Productpossible amidotransferase
CommentsML1573c, len: 249 aa. Possible amidotransferase (EC 6.3.5.-). Similar to several e.g. Mycobacterium tuberculosis Rv2859c TR:O33341. Also similar in regions to Dictyostelium discoideum GMP synthase (EC 6.3.5.2) (glutamine amidotransferase) SW:GUAA_DICDI (P32073) (718 aa), Fasta scores: E(): 0.0045, 26.7% identity in 176 aa overlap. Contains Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS18989891899738-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1573c|ML1573c
VDLSGSRPVVGLTAYLEQVHTGLWDVPAGYLPADYFQGVAMAGGIAVLLPPQPVDPEIAGLALDGLDGLVITGGYDVDPATYGQRPHPSTDEPRTTRDSWEFALFEAALQRGLPVLGICRGAQLLNIALGGTLHQHLPEVIGHSKHWVGNAVFNNLLVRTVPGTRLAAVLGEFVEARCYHHQSIDKLGDGLVVSAWDADGVVEAVELPGDAFVLGVQWHPEKALSDLRLFTAIVDAACRYANSRCVEYS
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