Gene ML1576c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) |
| Comments | ML1576c, len: 285 aa. Probable mapB, methionine aminopeptidase (EC 3.4.11.18). Highly similar to many methionine aminopeptidases responsible for removing the amino-terminal methionine from many nascent proteins e.g. Escherichia coli SW:AMPM_ECOLI (P07906) (264 aa), Fasta scores: E(): 0, 51.4% identity in 247 aa overlap and Mycobacterium tuberculosis Rv2861c SW:AMPM_MYCTU (O33343) (285 aa), Fasta scores: E(): 0, 89.8% identity in 283 aa overlap. Contains Pfam match to entry PF00557 Peptidase_M24, metallopeptidase family M24. Contains PS00680 Methionine aminopeptidase subfamily 1 signature. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 1900892 | 1901749 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1576c|mapB
MPARTALSPGFLSPTLPVPAWIPRPEYVGKPTAQEGSESWVQTPEVVEKMRVAGRIAAGALTEAGKAVAPGVTTDELDRIVHEYMVNHGAYPSTLGYKGYPKSCCTSLNEVICHGIPDSTVIADGDIVNIDVTAYIDGVHGDTNATFLSGDVSESHRLLVERTREATMRAINAVKPGRALSIIGRVIESYANRFGYNVVRHFTGHGIGTTFHNGLVVLHYDQPFVTTIMQPGMTFTIEPMINLGTLDYEVWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTVQ
Bibliography
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