Gene ML1590c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefrr
Gene length558 bp
IdentifierML1590c
Location 1914874 bp
Protein summary information
Molecular mass20891.8 Da
Isoelectric point5.43
Protein length186 amino acids
Structural information
PFAMPF01765
Orthologs
M. tuberculosis H37RvRv2882c
M. lepromatosis Mx1-22AMLPM_1590
Cross-references
UniProtO33046
Gene OntologyTranslational termination, Cytoplasm
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductRIBOSOME RECYCLING FACTOR FRR (RIBOSOME RELEASING FACTOR) (RRF)
CommentsML1590c, len: 185 aa. Probable frr, ribosome recycling factor. Highly similar to many ribosome releasing factors, involved in the release of ribosomes from messenger RNA at the termination of translation, e.g. Escherichia coli SW:RRF_ECOLI (P16174) (430 aa), BlastP Expect 9.8 and Mycobacterium tuberculosis Rv2882c SW:RRF_MYCTU (Q10794) (185 aa), Fasta scores: E(): 0, 90.8% identity in 185 aa overlap. Contains Pfam match to entry PF01765 RRF, Ribosome recycling factor.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19148741915431-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1590c|frr
MIDEALFDAEEKMEKAVSVAREDLSMIRTGRANPGMFSRLVIDYYGSATPITQLASINVPEARLVVIKPYDAIQLHAIETAIRNSDLGVNPSNDGTLIRVAVPQLTEERRRELVKQAKCKGEDAKVSVRNIRRKVMEELHRIRKDGEAGEDEVSRAEKDLDKTTHQYVIQIDELVKHKEGELLEV
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