Gene ML1600c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namexerC
Gene length894 bp
IdentifierML1600c
Location 1924851 bp
Protein summary information
Molecular mass32147.8 Da
Isoelectric point11.05
Protein length298 amino acids
Structural information
PFAMPF00589, PF02899
Orthologues
M. tuberculosisRv2894c
Cross-references
UniProtQ9CBU0
Gene OntologyDna integration, Cell cycle, Cell division, Chromosome segregation, Cytoplasm, Transposition, dna-mediated, Tyrosine-based site-specific recombinase activity, Dna binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE INTEGRASE/RECOMBINASE XERC
CommentsML1600c, len: 297 aa. Probable xerC, integrase/recombinase. Highly similar to many integrase/recombinases including: Escherichia coli XerD, involved in site-specific recombination of plasmid ColE1 and chromosome partitioning, SW:XERD_ECOLI (P21891) (298 aa), Fasta scores: E(): 0, 41.5% identity in 301 aa overlap and Mycobacterium tuberculosis Rv2894c SW:YS94_MYCTU (Q10815) (298 aa), Fasta scores: E(): 0, 85.1% identity in 296 aa overlap. Also similar to ML1365 from M. leprae. Contains Pfam match to entry PF00589 Phage_integrase, 'Phage' integrase family.
Functional categoryInsertion seqs and phages
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19248511925744-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1600c|xerC
VAILDEFDEHLALRCGRSEHTRRAYLGDLRSLLTHLEGRGSRLDQLSLPVLRSWLATAAGAGAARTTLARRISAVKAFTAWAKWRGQLAADPAARLQVPRAYRTLPAVLRQDQALQIMAAAKSGAEQGDPLALRDRLIVEMLYATGIRVSELCGLDIDDVDTRHRLVRVLGKGNKQRTAPFGVPAADALRGWLDDGRPALVTVESGPALLLGSRGRRLDVRQARTVVHQTVAVVAGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVSRLRVVHDQAHPRA
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