Gene ML1653 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefabD
Gene length915 bp
IdentifierML1653
Location 1993522 bp
Protein summary information
Molecular mass31311.7 Da
Isoelectric point4.45
Protein length305 amino acids
Structural information
PFAMPF00698
Orthologs
M. tuberculosis H37RvRv2243
M. lepromatosis Mx1-22AMLPM_1653
Cross-references
UniProtO69476
Gene OntologyMetabolic process, Transferase activity, Binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductMALONYL CoA-ACYL CARRIER PROTEIN TRANSACYLASE FABD (Malonyl CoA:AcpM acyltransferase) (MCT)
CommentsML1653, len: 304 aa. Probable fabD, malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39). Similar to many malonyl CoA-acyl carrier protein transacylases involved in fatty acid biosynthesis, including: Salmonella typhimurium SW:FABD_SALTY (O85140) (308 aa), Fasta scores: E(): 1.6e-19, 32.7% identity in 303 aa overlap and Mycobacterium tuberculosis Rv2243 SW:FABD_MYCTU (Q10501) (302 aa), Fasta scores: E(): 0, 82.2% identity in 304 aa overlap. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19935221994436+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1653|fabD
VIALLAPGQGSQTEGMLSPWLGLPGAADQIATWSKASGLDLVRLGTTASTEEITDTAVAQPLIVATTLLAHQELAKHALFENALDNLIVAGHSVGEIAAYSIAGVIAADDAVALAATRGAEMAKACAIEPTGMSAVLGGDEADVLNRLEELDLVPANRNAAGQIVAAGRLTALEKLAEDPPARARVRALDVAGAFHTEFMTAALDGFAEAAASITIAEPIAMLLSNRDGKPVASAATGMETLISQLTHPARWDLCNVTLREHNVTAIVELPPAGALTGIAKRELREVTTCAVKSPTDLDKLANL
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