Gene ML1691c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) |
| Comments | ML1691c, len: 336 aa. Probable leuB, 3-isopropylmalate dehydrogenase (EC 1.1.1.85). Highly similar to 3-isopropylmalate dehydrogenases, involved in leucine biosynthesis, from Mycobacterium bovis SW:LEU3_MYCBO (P94929) (336 aa), Fasta scores: E(): 0, 83.9% identity in 336 aa overlap and Mycobacterium tuberculosis Rv2995c SW:LEU3_MYCTU (P95313) (336 aa), Fasta scores: E(): 0, 83.9% identity in 336 aa overlap. Contains Pfam match to entry PF00180 isodh, Isocitrate and isopropylmalate dehydrogenases. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2037162 | 2038172 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1691c|leuB
MKLAIIGGDGIGPEVVAQAVKILDVVLPGVQKTTYDLGARRYHTTGELLPESVLAELREHDAILLGAVGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVNSLLAGKPDIDFVVVREGTEGPYTGTGGAIRVGTPNEVATEVSVNTAFGVRRVVQDAFERARQRRKHLTLVHKNNVLTYAGTLWCRIVQEVGEKYPDVEVVYQHIDAATIYLVTEPSRFDVIVTDNLFGDIITDLAAAVCGGIALAASGNIDATRTNPSMFEPVHGSAPDIAGQGIADPTAAIMSLALLLAHLGEDEPAARLDQAVASYLATRGNGRFSTGEVGERIAAAL
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