Gene ML1701c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepfkA
Gene length1032 bp
IdentifierML1701c
Location 2052005 bp
Protein summary information
Molecular mass37001.9 Da
Isoelectric point6.32
Protein length344 amino acids
Structural information
PFAMPF00365
Orthologues
M. tuberculosisRv3010c
Cross-references
UniProtO33106
Gene Ontology6-phosphofructokinase complex, Atp binding, Fructose 6-phosphate metabolic process, Glycolysis, Magnesium ion binding, 6-phosphofructokinase activity
Enzyme Classification2.7.1.11
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE)
CommentsML1701c, len: 343 aa. Probable pfkA, 6-phosphofructokinase (EC 2.7.1.11). Highly similar to many 6-phosphofructokinases including: Streptomyces coelicolor SW:K6PF_STRCO (O08333) (342 aa), Fasta scores: E(): 0, 56.5% identity in 345 aa overlap and Mycobacterium tuberculosis Rv3010c SW:K6PF_MYCTU (O53257) (343 aa), Fasta scores: E(): 0, 90.4% identity in 343 aa overlap. Contains 2 Pfam matches to entry PF00365 PFK, Phosphofructokinase. Contains PS00433 Phosphofructokinase signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20520052053036-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1701c|pfkA
MRIGILTGGGDCPGLNAVIRAIVRTCDARYGSSVVGFQDGWRGLLENRRMQLCNDDRNDRLLAKGGTMLGTAHVHPDKLRAGLHQIKQTLDDNGIDVLIPIGGEGTLTAAHWLSQEDVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEAIDRLHSTAESHQRVMLVEVMGRHAGWIALSSGLASGAHMTLIPEQPFDVEEVCCLVKRRFQRGDSHFICVVAEGAKPVPGSITLRQGGMDEFGHERFTGVAAQLGAEVEKRINKDVRVTVLGHVQRGGTPTAFDRVLATRFGVNAADASHAGEYGQMVSLRGQDIGRVPLEDAVRQLKLVPESRYDDAAAFFG
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