Gene ML1724c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE ENOYL-CoA HYDRATASE ECHA17 (CROTONASE) (UNSATURED ACYL-CoA HYDRATASE) (ENOYL HYDRASE) |
| Comments | ML1724c, len: 252 aa. Probable echA17, enoyl-CoA hydratase (EC 4.2.1.17). Similar to several proposed enoyl-CoA hydratases including: Rhizobium meliloti SW:ECHH_RHIME (Q52995) (257 aa), Fasta scores: E(): 1.8e-19, 34.7% identity in 225 aa overlap, Clostridium acetobutylicum SW:CRT_CLOAB (P52046) (261 aa), Fasta scores: E(): 1.7e-17, 27.9% identity in 240 aa overlap and Mycobacterium tuberculosis Rv3039c TR:O53286 (EMBL:AL021287) (254 aa), Fasta scores: E(): 0, 85.6% identity in 243 aa overlap. Also similar to ML2402 from M. leprae. Contains Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase family. |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2080798 | 2081556 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML1724c|echA17
MSEFVNIVVSDGSQDAGLAILLLSRPPTNAMTRQFYREIAMAADELGRRDDVAAVILFGGHDIFSAGDDMQELRTLTAVEAGVAAEVRRQAVDAVATIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILADLVPDGDGLARLTRVAGVSRAKDLVFSGRFFDAAEALALGLIDDMVAPDDVYDIAAAWARRFLDGLPHALAAAKAGINEVFDLEPAERIAAERRRYVEVFAAAQPSLLLGGCD
Bibliography
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