Gene ML1727c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameserB2
Gene length1236 bp
IdentifierML1727c
Location 2083355 bp
Protein summary information
Molecular mass43530.0 Da
Isoelectric point4.88
Protein length412 amino acids
Structural information
PFAMPF00702, PF01842
Orthologues
M. tuberculosisRv3042c
Cross-references
UniProtQ9CBQ6
Gene OntologyAmino acid binding, Phosphoserine phosphatase activity, L-serine biosynthetic process
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOSPHOSERINE PHOSPHATASE SERB2 (PSP) (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSPASE)
CommentsML1727c, len: 411 aa. Probable serB2, Phosphoserine phosphatase (EC 3.1.3.3). Similar in the C-terminus to many phosphoserine phosphatases including: Escherichia coli SW:SERB_ECOLI (P06862) (322 aa), Fasta scores: E(): 1.7e-29, 38.5% identity in 309 aa overlap and Mycobacterium tuberculosis Rv3042c TR:O53289 (EMBL:AL021287) (409 aa), Fasta scores: E(): 0, 86.3% identity in 408 aa overlap. Contains Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20833552084590-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1727c|serB2
VNTPPKVSVLITVTGVDQPGVTSALFAVLSRHGGELLNVEQVVIRGRLTLGVLVLCPPEVAAYTALRDDVQAAIRRVGLDVTIERSDDLPIIREPSTHTIFVLGRPITARAFGAVAREVAALDVNIDVIRGISDYPVTGLELRVSAPLEAAGSLRTALNRVATEEHVDVAVEGYGLARRIKRLIVFDVDSTLVQGEVIEMLAARAGAQGTVAAITEAAMRGELDFAESLQQRVATLAGLPVTVVDEVANQLQLMPGARTTLRTLRRLGFRCGVVSGGFRRIIEPLAHELMLDFVAANELEIVDGILTGRVVGTIVDRPGKAKALRYFSEQAGVPMEQTVAVGDGANDIDMLTAAGLGIAFNAKPALRAVADASLSHPYLDTVLFVLGVTRGEIEAADAADGGVRRVEIPPD
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